AZD4045

A Modular, Phase I/​II, Multicentre Study to Evaluate AZD4045, in Participants With Relapsed or Refractory Multiple Myeloma

What will happen during the trial?

This modular study aims to evaluate the safety, tolerability, preliminary efficacy, and cellular kinetics of AZD4045 in participants with relapsed or refractory multiple myeloma (RRMM), and determine the recommended Phase 2 dose of AZD4045. Module 1 consists of AZD4045 as a monotherapy and in association with daratumumab and aldesleukin.

More Information

Trial Status
Not yet accepting
Trial Phase
Phase 1/2
Enrollment
101 patients (estimated)
Sponsors
AstraZeneca
Tags
CAR T Cell (Allogeneic), T Cell Engager (TCE), B-Cell Maturation Antigen (BCMA)
Trial Type
Treatment
Last Update
SparkCures ID
2276
NCT Identifier
NCT07681596

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