Holden Comprehensive Cancer Center - University of Iowa

University of Iowa Hospitals and Clinics

Iowa City, IA

Sorting 11 by

Accepting patients

QUINTESSENTIAL

Phase 2 Study of BMS-986393, a GPRC5D-directed CART-Cell Therapy, in Participants with Relapsed or Refractory Multiple Myeloma
  • CAR T Cell
  • GPRC5D
  • Phase 2

Accepting patients

MagnetisMM-20

A Clinical Trial of Four Medicines (Elranatamab Plus Carfilzomib and Dexamethasone or Maplirpacept) in People With Relapsed Refractory Multiple Myeloma
  • Bispecific Antibody
  • BCMA
  • Phase 1
  • Has results

Accepting patients

DURGA-1

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)
  • CAR T Cell
  • BCMA
  • CD19
  • Phase 1/2
  • Has results

Accepting patients

TRIlogy-3

A Phase 2, Open-label Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) Who Have Received at Least 3 Prior Lines of Therapy Including a PI, an IMiD, and an Anti-CD38 Antibody
  • Trispecific Antibody
  • GPRC5D
  • BCMA
  • Phase 2

Accepting patients

TRIlogy-4

A Phase 3 Randomized Study Comparing JNJ-79635322 and an Anti-BCMAxCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma Who Have Received at Least 3 Prior Lines of Therapy Including a PI, an IMiD, and an Anti CD38 Antibody
  • T Cell Engager (TCE)
  • Trispecific Antibody
  • BCMA
  • CD3
  • GPRC5D
  • Randomization
  • Phase 3

Not yet accepting

Sirolimus + Teclistamab or Talquetamab

Impact of Sirolimus Pre-conditioning on T Cell Activity and T-cell Engaging Bispecific Antibody Efficacy in Multiple Myeloma
  • Mammalian Target of Rapamycin (mTOR) Inhibitor
  • Cytoprotectant
  • Immunosuppressant
  • Phase 1

Accepting patients

LimiTec

Phase 2, Single-Arm, Non-Inferiority Study Of Limited-Duration Teclistamab For Relapsed Refractory Multiple Myeloma
  • Bispecific Antibody
  • BCMA
  • Phase 2
  • Has results

Accepting patients

DURGA-2

A Phase I, Open-label, Multicenter Study to Evaluate the Safety, Tolerability, Cellular Kinetics, Immunogenicity, Pharmacodynamics, and Preliminary Efficacy of AZD0120 in Participants With Multiple Myeloma
  • CAR T Cell
  • CD19
  • BCMA
  • High Risk
  • Phase 1

Accepting patients

Sleep Apnea

Sleep Apnea in Patients With MGUS and Multiple Myeloma
  • Observational Trial

Accepting patients

FASTER

Frontline T-cell Engager vs Autologous Stem Cell Transplant and Measurable Residual Disease (MRD)-Guided Sequential Intensification thERapy in Multiple Myeloma (FASTER)
  • Autologous Stem Cell Transplant
  • Bispecific Antibody
  • BCMA
  • Phase 2
1 hidden based on your filters.Show All