MagnetisMM-20
Phase 1B Study Evaluating Elranatamab in Combination with Carfilzomib/Dexamethasone or in Combination with PF-07901801 (maplirpacept) in Relapsed/Refractory Multiple Myeloma
What's the purpose of the trial?
The goal of this study is to evaluate the best dose, safety, and effectiveness of elranatamab when combined with carfilzomib and dexamethasone, and to evaluate the best dose, safety and effectiveness of PF-07901801 (maplirpacept)when combined with elranatamab in participants with relapsed/refractory multiple myeloma.
Accepting patients
Participating Centers
There are 6 centers participating in this trial. Enter a location below to find the closest center.
Experimental Treatments
Learn more about the experimental treatments being evaluated in this clinical trial.
- Carfilzomib Carfilzomib is a kind of medication called a proteasome inhibitor that interferes with the growth and spread of cancer cells in the body. Carfilzomib is used in the treatment of multiple myeloma.
- Dexamethasone is a corticosteroid that prevents the release of substances in the body that cause inflammation, and is given in conjunction with some cancer treatments.
- Elranatamab is a B-Cell Maturation Antigen (BCMA) CD-3 bispecific antibody being tested in multiple myeloma
Arms / Cohorts
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