Massachusetts General Hospital

Not yet accepting

KarMMa-9

Phase 3 Clinical Trial Comparing the Efficacy and Safety of Idecabtagene Vicleucel with Lenalidomide Maintenance to Approved Lenalidomide Maintenance Alone in Patients with Newly Diagnosed Multiple Myeloma Who Have Suboptimal Response After Stem Cell Transplant
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  • CAR T Cell
  • Immunomodulatory Drug
  • BCMA
  • Randomization
  • Phase 3

Accepting patients

MonumenTAL-3

Phase 3 Clinical Trial Comparing the Efficacy of an Investigational Medication Combined with Daratumumab or Daratumumab and Pomalidomide Versus Daratumumab, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma.
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  • Bispecific Antibody
  • GPRC5D
  • Randomization
  • Phase 3

Not currently accepting

KarMMa-2

Phase 2 Clinical Trial Studying the Safety and Efficacy of bb2121 in Participants with Relapsed and Refractory Multiple Myeloma or Clinical High-Risk Multiple Myeloma
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  • CAR T Cell
  • BCMA
  • High Risk
  • Phase 2

Accepting patients

Bone Marrow & Kidney Transplant

Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders (BMT)
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  • Allogeneic Stem Cell Transplant
  • Phase 2

Accepting patients

Daratumumab Combination Therapy

Daratumumab, Carfilzomib, Pomalidomide, Dexamethasone In MM
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  • Monoclonal Antibody
  • Proteasome Inhibitor
  • CD38
  • Phase 2

Accepting patients

TriPRIL CAR T

TriPRIL CAR T Cells in Multiple Myeloma
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  • CAR T Cell
  • APRIL
  • BCMA
  • Phase 1

Not yet accepting

ISABELA

A Phase II Study of ISABELA: Isatuximab, Belantamab Mafodotin, Pomalidomide, and Dexamethasone in Relapsed and Refractory Multiple Myeloma
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  • Monoclonal Antibody
  • CD38
  • Quadruplet Therapy
  • Phase 2

Accepting patients

Elranatamab as Consolidation

A Phase 2 Study of Elranatamab as Consolidation After Idecabtagene Vicleucel in Relapsed Refractory Multiple Myeloma
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  • Bispecific Antibody
  • BCMA
  • CD3
  • Phase 2

Accepting patients

CaMMouflage

A Phase 1, Multicenter, Open-Label Study of CB-011, a CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma (CaMMouflage Trial)
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  • CAR T Cell (Allogeneic)
  • BCMA
  • Phase 1

Not yet accepting

CARTITUDE-6

A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (CARTITUDE-6)
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  • Autologous Stem Cell Transplant
  • CAR T Cell
  • BCMA
  • Phase 3
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