MMSET Inhibitor

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma

What's the purpose of the trial?

A Phase I study to evaluate the safety of a novel, orally available, selective, and potent small molecule inhibitor of the histone lysine methyl transferase MMSET (also known as NSD2/WHSC1) to prevent the dimethylation of H3K36 in adult patients with relapsed or refractory multiple myeloma (RRMM).

Trial status

Accepting patients

Phase
Phase 1
Enrollment
60
Last Updated
2 months ago
Patient Screener

Participating Centers

There are 14 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

Learn more about the experimental treatments being evaluated in this clinical trial.

  • KTX-1001 is a kind of drug called an MMSET Catalytic Inhibitor. KTX1001 may work by slowing the growth of cancer cells that express the MMSET protein.

Arms / Cohorts

Explore eligibility, treatments and learn more about potential cohorts.

Accepting patients

Dose Escalation: KTX-1001

Not yet accepting

Dose Expansion: KTX-1001

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