Abramson Cancer Center - University of Pennsylvania (UPENN)

University of Pennsylvania

Philadelphia, PA

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Accepting patients

CARTITUDE-2

Phase 2, Open-Label Study Evaluating the Use of an Investigational CAR-T Cell therapy in Participants with Multiple Myeloma
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  • CAR T Cell
  • BCMA
  • Phase 2

Not yet accepting

MonumenTAL-8

A Phase 2, Open-Label, Multicenter Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma
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  • Bispecific Antibody
  • CAR T Cell
  • BCMA
  • GPRC5D
  • Phase 2

Accepting patients

DRAMMATIC

S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration (DRAMMATIC)
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  • Monoclonal Antibody
  • CD38
  • Maintenance
  • Phase 3

Accepting patients

Teclistamab

Phase 2, Single-Arm, Non-Inferiority Study Of Limited-Duration Teclistamab For Relapsed Refractory Multiple Myeloma
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  • Bispecific Antibody
  • BCMA
  • Phase 2

Accepting patients

Cevostamab after CAR-T Cell Therapy

Phase 2 Study of Cevostamab Consolidation Following BCMA CAR T Cell Therapy for Relapsed/Refractory Multiple Myeloma
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  • Bispecific Antibody
  • FCRH5
  • Post-CAR T
  • Phase 2

Accepting patients

Investigational Cord Blood Units

Safety Study of Unlicensed, Investigational Cord Blood Units Manufactured by the National Cord Blood Program (NCBP) for Unrelated Transplantation
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  • Allogeneic Stem Cell Transplant
  • Cord Blood
  • Phase 2

Accepting patients

Tasquinimod

Tasquinimod for the Treatment of Relapsed or Refractory Myeloma
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  • S100A9 Inhibitor
  • Phase 1

Accepting patients

Belantamab Mafodotin

Study of Belantamab Mafodotin as Pre- and Post-autologous Stem Cell Transplant and Maintenance for Multiple Myeloma
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  • Antibody Drug Conjugate (ADC)
  • Autologous Stem Cell Transplant
  • BCMA
  • Maintenance
  • Phase 2

Accepting patients

CART 38

Phase 1 Study of Lintivirally Transduced T Cells Engineered to Contain Anti-CD38 Linked to TCRζ and 4-1BB Signaling Domains in Subjects With Acute Myeloid Leukemia and Multiple Myeloma
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  • CAR T Cell
  • CD38
  • Phase 1

Accepting patients

JNJ-79635322

Phase 1, First-in-Human, Dose Escalation Study of JNJ-79635322, a Trispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated AL Amyloidosis
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  • BCMA
  • GPRC5D
  • Tri-specific Antibody
  • Phase 1
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