JNJ-79635322

Phase 1, First-in-Human, Dose Escalation Study of JNJ-79635322, a Trispecific Antibody, in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated AL Amyloidosis

What's the purpose of the trial?

The primary purpose of this study is to identify the recommended phase 2 dose (RP2D\[s\]) and schedule(s) to be safe for JNJ-79635322 in Part 1 (dose escalation), and to characterize the safety and tolerability of JNJ-79635322 at the RP2D(s) selected and in disease subgroups in Part 2 (dose expansion).

Trial status

Accepting patients

Phase

Phase 1

Enrollment

180

Last Updated

1 week ago

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Participating Centers

There are 9 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

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JNJ-79635322 is a trispecific antibody that targets BCMA and GPRC5D on cancer cells, and CD3 on our own immune cells.

Arms / Cohorts

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Accepting patients

Dose Escalation

Accepting patients

Dose Expansion

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