LINKER-MM5

A Study to Compare Linvoseltamab Monotherapy and Linvoseltamab + Carfilzomib Combination Therapy With Standard-of-Care Combination Regimens in Adult Participants With Relapsed/​Refractory Multiple Myeloma (RRMM) (LINKER-MM5)

What will happen during the trial?

The aim of this study is to see if the safety and efficacy of linvoseltamab alone or in combination with carfilzomib can deliver better outcomes (deeper and longer responses that help extend life) than standard treatment options. The study is looking at several other research questions, including:

  • What side effects may happen from taking the study drug
  • How much study drug is in the blood at different times
  • Whether the body makes antibodies against the study drug (which could make the drug less effective or could lead to side effects)

More Information

Trial Status
Accepting patients
Trial Phase
Phase 3
Enrollment
915 patients (estimated)
Tags
Bispecific Antibody, T Cell Engager (TCE), B-Cell Maturation Antigen (BCMA), CD3
Trial Type
Treatment
Last Update
SparkCures ID
2245
NCT Identifier
NCT07222761

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