Pre and Post Transplant Elranatamab

Pre-transplant Purging and Post-transplant MRD-guided Maintenance Therapy With Elranatamab in Patients With High-risk Multiple Myeloma

What's the purpose of the trial?

To learn if giving elranatamab before and after an autologous stem cell transplant (ASTC) can help to control newly diagnosed, high-risk MM. An ASTC is a type of transplant in which a person's own stem cells are collected, preserved, and returned to them.
Trial status

Accepting patients

Phase
Phase 2
Enrollment
40
Last Updated
3 months ago

Participating Centers

There is one center participating in this trial. Enter a location below to view the distance.

Experimental Treatments

Learn more about the experimental treatments being evaluated in this clinical trial.

  • Busulfan is a chemotherapy cancer medication that interferes with the growth and spread of cancer cells in the body, and may be used in the treatment of many different cancers.
  • Elranatamab is a B-cell Maturation Antigen (BCMA)-CD3 bispecific antibody being tested in multiple myeloma.
  • Granulocyte Colony-Stimulating Factor is a glycoprotein used to stimulate the bone marrow to help with granulocyte and stem cell production.
  • Lenalidomide is an oral immunomodulatory drug that may help the immune system kill cancer cells. It may also prevent the growth of new blood vessels that tumors need to grow.
  • Melphalan is a chemotherapy medication used in the treatment of different cancers.
  • Plerixafor is a bone marrow stimulating medication that is often used to help move stem cells into peripheral blood to help with cell collection before bone marrow transplantation.

Arms / Cohorts

Explore eligibility, treatments and learn more about potential cohorts.

Accepting patients

Elranatamab

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