Triplet Induction + 1 or 2-Drug Maintenance

A Phase III Randomized Trial for Newly Diagnosed Multiple Myeloma (NDMM) Patients Considered Frail or in a Subset of "Intermediate Fit" Comparing Upfront Three-Drug Induction Regimens Followed by Double or Single-Agent Maintenance

Arms / Cohorts

Active Comparator:Arm I: Bortezomib + Lenalidomide + Dexamethasone + Lenalidomide Maintenance

Accepting patients

Experimental:Arm II: Daratumumab + Lenalidomide + Dexamethasone + Lenalidomide Maintenance

Accepting patients

Experimental:Arm III: Daratumumab + Lenalidomide + Dexamethasone + Daratumumab and Lenalidomide Maintenance

Accepting patients

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