LINKER-MM4

Phase 1/2 Study of Linvoseltamab (Anti-BCMA X Anti-CD3 Bispecific Antibody) in Previously Untreated Patients With Symptomatic Multiple Myeloma

What will happen during the trial?

The primary objectives of the study are:

For Phase 1

  • To find out if linvoseltamab is safe and well tolerated
  • To find out what the most appropriate dosing schedule would be for future clinical trials

For Phase 2

  • To find out if it works to treat multiple myeloma

The secondary objectives of the study are:

For Phase 1 and 2

  • To find out how linvoseltamab moves throughout the body over time (pharmacokinetics)
  • To find out how much B-cell maturation antigen (BCMA) participants have in their blood
  • To find out if the participants' immune systems respond to linvoseltamab.

More Information

Trial Status
Accepting patients
Trial Phase
Phase 1/2
Enrollment
132 patients (estimated)
Sponsors
Regeneron Pharmaceuticals
Tags
Bispecific Antibody, B-Cell Maturation Antigen (BCMA), CD3
Trial Type
Treatment
Last Update
3 weeks ago
SparkCures ID
1479
NCT Identifier
NCT05828511

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