EXCALIBER-Maintenance

Phase 3 Clinical Trial Comparing Iberdomide VS Lenalidomide as Maintenance Therapy Following Autologous Stem Cell Transplant in Participants with Newly Diagnosed Multiple Myeloma

What's the purpose of the trial?

The goal of this clinical trial is to learn more about the safety and efficacy of an investigational drug called Iberdomide when used as maintenance therapy, and to compare its safety and efficacy to Lenalidomide maintenance therapy. 

Trial status

Accepting patients

Phase
Phase 3
Enrollment
1216
Last Updated
6 days ago
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Participating Centers

There are 44 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

Learn more about the experimental treatments being evaluated in this clinical trial.

  • Iberdomide is a Cereblon (CRBN) binding compound currently under clinical investigation for multiple myeloma.
  • Lenalidomide is an oral immunomodulatory drug that may help the immune system kill cancer cells. It may also prevent the growth of new blood vessels that tumors need to grow.

Arms / Cohorts

Explore eligibility, treatments and learn more about potential cohorts.

Not currently accepting

Stage 1, Arm A1

Not currently accepting

Stage 1, Arm A2

Not currently accepting

Stage 1, Arm A3

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