EZM0414

A Study in Subjects With Relapsed/Refractory Multiple Myeloma and Relapsed/Refractory Diffuse Large B-Cell Lymphoma

What's the purpose of the trial?

This is a first-in-human (FIH), 2-part, open-label, multi-center, Phase 1/1b safety, tolerability, pharmacokinetics (PK), and efficacy study of oral SETD2 inhibitor, EZM0414, in subjects with relapsed/refractory (R/R) Multiple Myeloma (MM) and R/R Diffuse Large B-Cell Lymphoma (DLBCL).

Trial status

Accepting patients

Phase
Phase 1
Enrollment
96
Last Updated
2 weeks ago
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Participating Centers

There are 9 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

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  • EZM0414 is a first-in-class, oral SETD2 inhibitor.

Arms / Cohorts

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Accepting patients

EZM0414

Not yet accepting

EZM0414 in Patients with t(4;14)

Not yet accepting

EZM0414 in Patients without t(4;14)

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