NK Cell Therapy With BHV-1100

Autologous Memory-like NK Cell Therapy With BHV-1100 (Formerly KP1237), Low Dose IL-2 in Multiple Myeloma Patients

What's the purpose of the trial?

This is an open-label single center Phase 1a/1b study with the primary objective of establishing the safety and exploring the efficacy of infusing the ex vivo combination product of cytokine induced memory-like (CIML) NK cells plus KP1237 and low dose IL-2 in newly diagnosed MM patients who have minimal residual disease (MRD+) in first remission prior to autologous stem cell transplant (ASCT).

Trial status

Accepting patients

Phase
Phase 1
Enrollment
25
Last Updated
1 month ago
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Participating Centers

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Experimental Treatments

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  • BHV-1100 is an antibody recruiting molecule that targets CD38.

Arms / Cohorts

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Accepting patients

BHV-1100

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