KPG-818

Safety, Tolerability and Pharmacokinetics Study of KPG-818 in Hematological Malignancies Subjects

What's the purpose of the trial?

This is a Phase 1 study to evaluate the safety, pharmacokinetics(PK), and preliminary clinical activity of KPG-818 as a single agent in adult subjects with selected hematological malignancies, including multiple myeloma (MM), mantle cell lymphoma (MCL), follicular lymphoma (FL), diffuse large B-cell lymphoma (DLBCL), indolent lymphoma, adult T-cell leukemia-lymphoma (ATL), or chronic lymphocytic leukemia (CLL).

Trial status

Accepting patients

Phase
Phase 1
Enrollment
56
Last Updated
2 months ago
Patient Screener

Participating Centers

There are 7 centers participating in this trial. Enter a location below to find the closest center.

Experimental Treatments

Learn more about the experimental treatments being evaluated in this clinical trial.

  • KPG-818 KPG-818 is a novel small molecule modulator of the CRBN E3 ubiquitin ligase complex CRL4-CRBN.

Arms / Cohorts

Explore eligibility, treatments and learn more about potential cohorts.

Accepting patients

KPG-818

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