Mayo Clinic (Rochester)

Not currently accepting

CARTITUDE-2

Phase 2, Open-Label Study Evaluating the Use of an Investigational CAR-T Cell therapy in Participants with Multiple Myeloma
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  • CAR T Cell
  • BCMA
  • Phase 2

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QUINTESSENTIAL

Phase 2 Study of BMS-986393, a GPRC5D-directed CART-Cell Therapy, in Participants with Relapsed or Refractory Multiple Myeloma
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  • CAR T Cell
  • GPRC5D
  • Phase 2

Not yet accepting

SUCCESSOR-1

Phase 3 Clinical Trial Evaluating the Safety and Effectiveness of Investigational Drug Mezigdomide in Combination with Bortezomib and Dexamethasone Compared to Pomalidomide, Bortezomib and Dexamethasone in Relapsed or Refractory Multiple Myeloma
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  • CELMoD
  • Randomization
  • Phase 3

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CA088-1005

A Phase 1, Multicenter, Open-label Study to Evaluate the Safety and Preliminary Efficacy of BMS-986393 in Novel Combinations in Participants With Relapsed and/or Refractory Multiple Myeloma and Determine the Recommended Dose for Each Add-on Investigational Component
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  • CAR T Cell
  • CELMoD
  • GPRC5D
  • Phase 1

Accepting patients

GCO12F CAR-T

A Phase 1b/2 Study of GC012F, a Chimeric Antigen Receptor T-cell (CAR T) Therapy Targeting CD19 and B-cell Maturation Antigen (BCMA) in Subjects With Relapsed/Refractory Multiple Myeloma
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  • CAR T Cell
  • BCMA
  • CD19
  • Phase 1/2

Accepting patients

DRAMMATIC

S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration (DRAMMATIC)
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  • Monoclonal Antibody
  • CD38
  • Maintenance
  • Phase 3

Not yet accepting

Unexplained Cytopenia Post-CAR-T Cell Therapy

Understanding the Mechanisms of Clonal and Non-Clonal Cytopenia Following CAR-T Therapy
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  • Post-CAR T
  • Pre-CAR T

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CARTITUDE-6

A Study of Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Ciltacabtagene Autoleucel Versus Daratumumab, Bortezomib, Lenalidomide and Dexamethasone (DVRd) Followed by Autologous Stem Cell Transplant (ASCT) in Participants With Newly Diagnosed Multiple Myeloma (CARTITUDE-6)
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  • Autologous Stem Cell Transplant
  • CAR T Cell
  • BCMA
  • Phase 3

Accepting patients

RedirecTT-1

A Phase 1b/2 Dose Escalation and Expansion Study of the Combination of the Bispecific T Cell Redirection Antibodies Talquetamab and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma
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  • Bispecific Antibody
  • GPRC5D
  • Phase 1/2

Accepting patients

ABBV-383

A Study to Assess Adverse Events of Intravenously (IV) Infused ABBV-383 in Adult Participants With Relapsed or Refractory Multiple Myeloma
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  • Bispecific Antibody
  • BCMA
  • Phase 1
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