Mayo Clinic (Rochester)

Rochester, MN

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Accepting patients

QUINTESSENTIAL

Phase 2 Study of BMS-986393, a GPRC5D-directed CART-Cell Therapy, in Participants with Relapsed or Refractory Multiple Myeloma
  • CAR T Cell
  • GPRC5D
  • Phase 2

Accepting patients

EXCALIBER - Maintenance

Phase 3 Clinical Trial Comparing Iberdomide VS Lenalidomide as Maintenance Therapy Following Autologous Stem Cell Transplant in Participants with Newly Diagnosed Multiple Myeloma
  • CELMoD
  • Randomization
  • Post-Autologous Stem Cell Transplant
  • Phase 3

Accepting patients

CA088-1005

A Study to Evaluate the Safety, Effectiveness and Tolerable Dose of Arlocabtagene Autoleucel (BMS-986393) in Novel Combinations in Participants With Relapsed and/​or Refractory Multiple Myeloma
  • CAR T Cell
  • GPRC5D
  • Phase 1
  • Has results

Accepting patients

MMSET Inhibitor

A Study of an MMSET Inhibitor in Patients With Relapsed and Refractory Multiple Myeloma
  • H3K36me2
  • Phase 1
  • Has results

Accepting patients

Etentamig

A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma
  • Bispecific Antibody
  • BCMA
  • Phase 1
  • Has results

Accepting patients

DURGA-1

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)
  • CAR T Cell
  • BCMA
  • CD19
  • Phase 1/2
  • Has results

Not yet accepting

Horizon Adaptive Platform

MMRC Horizon One: RRMM (MMRC-099)
  • Bispecific Antibody
  • BCMA
  • CD3
  • Randomization
  • Phase 2

Accepting patients

Linvoseltamab

A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Patients With Multiple Myeloma That is Resistant to Current Standard of Care Treatments
  • Bispecific Antibody
  • BCMA
  • Phase 1
  • Has results

Accepting patients

Horizon Two

Horizon Two: HR NDMM (MMRC-100)
  • T Cell Engager (TCE)
  • Bispecific Antibody
  • BCMA
  • CD3
  • Randomization
  • High Risk
  • Maintenance
  • Phase 2

Accepting patients

Etentamig for Newly Diagnosed Patients

Phase 2/3, Multicenter, Randomized, Open-Label Study Evaluating the Efficacy and Safety of Etentamig and Daratumumab (Etentamig+D) Compared to Daratumumab, Lenalidomide, and Dexamethasone (DRd) in Subjects With Newly Diagnosed Multiple Myeloma Not Eligible for Transplant
  • Bispecific Antibody
  • CD3
  • BCMA
  • Randomization
  • Phase 2/3
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