Barbara Ann Karmanos Cancer Institute

Wayne State University

Detroit, MI

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Accepting patients

Horizon Adaptive Platform

MMRC Horizon One: RRMM (MMRC-099)
  • Bispecific Antibody
  • BCMA
  • CD3
  • Randomization
  • Phase 2

Accepting patients

Linvoseltamab

A Study to Examine the Effects of Novel Therapy Linvoseltamab in Combination With Other Cancer Treatments for Adult Patients With Multiple Myeloma That is Resistant to Current Standard of Care Treatments
  • Bispecific Antibody
  • BCMA
  • Phase 1
  • Has results

Accepting patients

CERVINO

A Phase 3, Multicenter, Randomized, Open Label Study of Etentamig Compared With Standard Available Therapies in Subjects With Relapsed or Refractory Multiple Myeloma (3L+ RRMM Monotherapy Study)
  • Bispecific Antibody
  • BCMA
  • Randomization
  • Phase 3

Accepting patients

LINKER-MM4

Phase 1/2 Study of Linvoseltamab (Anti-BCMA X Anti-CD3 Bispecific Antibody) in Previously Untreated Patients With Symptomatic Multiple Myeloma
  • Bispecific Antibody
  • BCMA
  • Phase 1/2
  • Has results

Accepting patients

IBEX

IBEX: Phase 2 Trial of Iberdomide + SQ Daratumumab as Post-Autologous Stem Cell Transplant Maintenance Therapy in Multiple Myeloma
  • CELMoD
  • Maintenance
  • Phase 2

Accepting patients

Isatuximab During Stem Cell Transplant

Isatuximab During Stem Cell Collection and Transplant in Patients With Multiple Myeloma and Lymphoma
  • Monoclonal Antibody
  • CD38
  • Post-Autologous Stem Cell Transplant
  • Pre-Autologous Stem Cell Transplant
  • Phase 2

Accepting patients

OPN-662

A Phase 1b, Dose Escalation/Dose Expansion, Multicenter, Open-Label Study to Assess the Safety and Tolerability of OPN-6602 Monotherapy and in Combination With Dexamethasone in Subjects With Relapsed and/or Refractory Multiple Myeloma
  • BET Inhibitor
  • Phase 1
  • Has results

Accepting patients

Triplet Induction + 1 or 2-Drug Maintenance

A Phase III Randomized Trial for Newly Diagnosed Multiple Myeloma (NDMM) Patients Considered Frail or in a Subset of "Intermediate Fit" Comparing Upfront Three-Drug Induction Regimens Followed by Double or Single-Agent Maintenance
  • Monoclonal Antibody
  • CD38
  • Randomization
  • Maintenance
  • Phase 3
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