University of Michigan Comprehensive Cancer Center

Rogel Cancer Center

Ann Arbor, MI

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Accepting patients

DREAMM-10

Phase 3 Clinical Trial Comparing the Safety and Efficacy of Belantamab Mafodotin, Lenalidomide and Dexamethasone Versus Daratumumab, Lenalidomide and Dexamethasone in Patients with Newly Diagnosed Multiple Myeloma who are Ineligible for Autologous Stem Cell Transplant
  • Antibody Drug Conjugate (ADC)
  • BCMA
  • Phase 3

Accepting patients

EXCALIBER - Maintenance

Phase 3 Clinical Trial Comparing Iberdomide VS Lenalidomide as Maintenance Therapy Following Autologous Stem Cell Transplant in Participants with Newly Diagnosed Multiple Myeloma
  • CELMoD
  • Randomization
  • Post-Autologous Stem Cell Transplant
  • Phase 3

Accepting patients

MonumenTAL-1

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma
  • Bispecific Antibody
  • GPRC5D
  • Phase 2

Accepting patients

MajesTEC-7

A Study to Compare Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) in Participants With Newly Diagnosed Multiple Myeloma (MajesTEC-7)
  • Bispecific Antibody
  • BCMA
  • Randomization
  • Phase 3
  • Has results

Accepting patients

DURGA-1

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)
  • CAR T Cell
  • BCMA
  • CD19
  • Phase 1/2
  • Has results

Accepting patients

CERVINO

A Phase 3, Multicenter, Randomized, Open Label Study of Etentamig Compared With Standard Available Therapies in Subjects With Relapsed or Refractory Multiple Myeloma (3L+ RRMM Monotherapy Study)
  • Bispecific Antibody
  • BCMA
  • Randomization
  • Phase 3

Accepting patients

Isatuximab in Combination With Novel Agents

Phase 1-2 UMBRELLA Trial Evaluating Isatuximab With or Without Dexamethasone in Combination With Novel Agents Compared to Isatuximab With Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma (RRMM) - Master Protocol
  • Monoclonal Antibody
  • CD38
  • Randomization
  • Phase 1/2

Accepting patients

Surzetoclax (ABBV-453)

A Phase 1/2, Open-Label, Platform Study to Evaluate Safety and Efficacy of the BCL-2 Inhibitor Surzetoclax (ABBV-453) Given as Monotherapy or in Combination With Antimyeloma Regimens in Subjects With Multiple Myeloma
  • BCL-2 Inhibitor
  • Phase 1/2
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