Alvin J. Siteman Cancer Center

Washington University Medical Campus

St. Louis, MO

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Accepting patients

QUINTESSENTIAL

Phase 2 Study of BMS-986393, a GPRC5D-directed CART-Cell Therapy, in Participants with Relapsed or Refractory Multiple Myeloma
  • CAR T Cell
  • GPRC5D
  • Phase 2

Accepting patients

MonumenTAL-1

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma
  • Bispecific Antibody
  • GPRC5D
  • Phase 2

Accepting patients

Etentamig with Iberdomide

Phase 1/2 Study of Etentamig in Combination With a CELMoD Agent for the Treatment of Patients With Relapsed/Refractory Multiple Myeloma
  • Bispecific Antibody
  • CELMoD
  • BCMA
  • Phase 1

Accepting patients

Sonrotoclax (BGB-11417)

A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
  • BCL-2 Inhibitor
  • Phase 1/2
  • Has results

Accepting patients

Horizon Adaptive Platform

MMRC Horizon One: RRMM (MMRC-099)
  • Bispecific Antibody
  • BCMA
  • CD3
  • Randomization
  • Phase 2

Accepting patients

Iberdomide vs. Observation Post Ide-Cel CAR-T

Iberdomide Versus Observation Off Therapy After Idecabtagene Vicleucel CAR-T for Multiple Myeloma
  • CELMoD
  • Maintenance
  • Randomization
  • Phase 2

Accepting patients

DoMMino-1

A Phase II, Open-Label, Multicenter Study of Inobrodib in Combination With Pomalidomide and Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
  • Bromodomain Inhibitor
  • CBP (CREB-binding Protein) Inhibitor
  • P300 Inhibitor
  • Phase 2

Accepting patients

Horizon Two

Horizon Two: HR NDMM (MMRC-100)
  • T Cell Engager (TCE)
  • Bispecific Antibody
  • BCMA
  • CD3
  • Randomization
  • High Risk
  • Maintenance
  • Phase 2

Accepting patients

SubQSA

A Single-arm, Open-label, Phase 2 Study Evaluating Subcutaneous Administration of Isatuximab, Administered by an On Body Delivery System, in Combination With Weekly Carfilzomib and Dexamethasone in Adult Participants With Relapsed and/or Refractory Multiple Myeloma (RRMM)
  • Monoclonal Antibody
  • CD38
  • Phase 2

Accepting patients

MRD-Guided Elranatamab Maintenance Therapy

Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance
  • Bispecific Antibody
  • CD3
  • BCMA
  • Maintenance
  • Phase 2
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