Huntsman Cancer Institute

University of Utah

Salt Lake City, UT

Not yet accepting

CARTITUDE-2

Phase 2, Open-Label Study Evaluating the Use of an Investigational CAR-T Cell therapy in Participants with Multiple Myeloma
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  • CAR T Cell
  • BCMA
  • Phase 2

Accepting patients

MonumenTAL-3

Phase 3 Clinical Trial Comparing the Efficacy of an Investigational Medication Combined with Daratumumab or Daratumumab and Pomalidomide Versus Daratumumab, Pomalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma.
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  • Bispecific Antibody
  • GPRC5D
  • Randomization
  • Phase 3

Not yet accepting

MonumenTAL-8

A Phase 2, Open-Label, Multicenter Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma
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  • Bispecific Antibody
  • CAR T Cell
  • BCMA
  • GPRC5D
  • Phase 2

Accepting patients

CAMMA-2

A Study Evaluating the Efficacy and Safety of Cevostamab in Prior B Cell Maturation Antigen (BCMA)-Exposed Participants With Relapsed/Refractory Multiple Myeloma (CAMMA 2)
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  • Bispecific Antibody
  • FCRH5
  • Phase 1/2

Accepting patients

ADVANCE

A Study of Daratumumab, Carfilzomib, Lenalidomide, and Dexamethasone in Patients With Newly-Diagnosed Multiple Myeloma (ADVANCE)
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  • Monoclonal Antibody
  • CD38
  • Phase 2

Not yet accepting

UltraFrailMM

Use of Isatuximab, Dexamethasone and Lenalidomide in a Go-Slow Fashion for Ultra-Frail Patients With Multiple Myeloma: A Phase 2 Multicenter Study
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  • Monoclonal Antibody
  • CD38
  • Phase 2

Accepting patients

CaMMouflage

A Phase 1, Multicenter, Open-Label Study of CB-011, a CRISPR-Edited Allogeneic Anti-BCMA CAR-T Cell Therapy in Patients With Relapsed/Refractory Multiple Myeloma (CaMMouflage Trial)
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  • CAR T Cell (Allogeneic)
  • BCMA
  • Phase 1

Accepting patients

DRAMMATIC

S1803, Lenalidomide +/- Daratumumab/rHuPh20 as Post-ASCT Maintenance for MM w/MRD to Direct Therapy Duration (DRAMMATIC)
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  • Monoclonal Antibody
  • CD38
  • Maintenance
  • Phase 3

Accepting patients

BGB-11417

A Phase 1b/2 Study of BGB-11417 in Monotherapy and in Various Combinations With Dexamethasone and Carfilzomib in Multiple Myeloma
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  • BCL-2 Inhibitor
  • Phase 1/2
  • Has results

Accepting patients

ABBV-383

A Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-383 in Combination With Anti-Cancer Regimens for the Treatment of Adult Participants With Relapsed/Refractory Multiple Myeloma
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  • Bispecific Antibody
  • Gamma-Secretase Inhibitor
  • BCMA
  • Phase 1
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