UNC Lineberger Comprehensive Cancer Center

University of North Carolina

Chapel Hill, NC

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Accepting patients

QUINTESSENTIAL

Phase 2 Study of BMS-986393, a GPRC5D-directed CART-Cell Therapy, in Participants with Relapsed or Refractory Multiple Myeloma
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  • CAR T Cell
  • GPRC5D
  • Phase 2

Accepting patients

STOMP

Phase 1B / 2 Study of Selinexor in Combination With Other Treatments for Relapsed/Refractory and Newly Diagnosed Multiple Myeloma.
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  • CELMoD
  • SINE
  • Phase 1/2
  • Has results

Accepting patients

Etentamig

A Study to Assess Adverse Events of Intravenously (IV) Infused ABBV-383 in Adult Participants With Relapsed or Refractory Multiple Myeloma
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  • Bispecific Antibody
  • BCMA
  • Phase 1
  • Has results

Not yet accepting

P-BCMA-ALLO1

P-BCMA-ALLO1 Allogeneic CAR-T Cells in the Treatment of Subjects With Multiple Myeloma (MM)
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  • CAR T Cell (Allogeneic)
  • BCMA
  • Phase 1
  • Has results

Accepting patients

Isatuximab in Frail Patients

Isatuximab Plus Lenalidomide and Dexamethasone for Frail and/or Much Older Patients With Newly Diagnosed Multiple Myeloma
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  • Monoclonal Antibody
  • CD38
  • Phase 2

Accepting patients

Iberdomide vs. Observation Post Ide-Cel CAR-T

Randomized Phase 2 Study of Iberdomide Maintenance Therapy Following Idecabtagene Vicleucel CAR-T in Multiple Myeloma Patients
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  • CELMoD
  • Maintenance
  • Randomization
  • Phase 2

Not currently accepting

Daratumumab Combination Induction

An Attenuated Schedule Dara-RVd Induction for Patients With Newly Diagnosed Multiple Myeloma Who Are Eligible for Autologous Stem Cell Transplantation
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  • Monoclonal Antibody
  • CD38
  • Quadruplet Therapy
  • Phase 2

Accepting patients

ISB 2001

A Phase 1, First-in-Human, Multicenter, Open-Label, Dose Escalation and Dose-Expansion Study of Single-Agent ISB 2001 in Subjects With Relapsed/Refractory Multiple Myeloma
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  • T Cell
  • Trispecific Antibody
  • BCMA
  • CD38
  • Phase 1
  • Has results

Accepting patients

LP-118

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory NHL, RT, MM, T-PLL, Acute Leukemia (AML, ALL), MDS, MDS/MPN, and MF
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  • BCL-2 Inhibitor
  • Bcl/xL Inhibitor
  • Phase 1
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